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Catalog Number | orb692029 |
---|---|
Category | Small Molecules |
Description | PK150 |
CAS Number | [2165324-62-7] |
MW | 394.68 |
SMILES | O=C(NC1C=C(C(F)(F)F)C(Cl)=CC=1)NC1C=C2OC(F)(F)OC2=CC=1 |
Formula | C15H8ClF5N2O3 |
Target | PK150 |
Note | For research use only |
Application notes | PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively. |
Expiration Date | 12 months from date of receipt. |