Omalizumab

• Catalog Number: orb1290233
• Category: Antibodies
• Description: Omalizumab biosimilar antibody
• Target: IGHE
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: IgG1-kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: PBS buffer pH 7.5
• Purity: > 95%
• Tested applications: ELISA
• Antibody Type: Biosimilar Antibody
• Source: CHO cells
• Biological Activity: Tonsillar B cells at a concentration of 1 × 106/mL in supplemented RPMI1640 were treated with 400 U/mL recombinant IL-4 plus 1 μg/mL anti-CD40 in the presence or absence of omalizumab or control antibody (human IgGκ). Omalizumab was reconstituted in sterile PBS at a concentration of 15 mg/mL. Dilutions of omalizumab were made in RPMI1640. In some instances the cells were pre-treated with FcR blocking reagent. At the indicated times, viable cell numbers were enumerated by their ability to exclude the dye trypan blue. Culture supernatant fluid was harvested for IL-6 quantification by ELISA.
• CAS Number: 242138-07-4
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: IGE25, olizumab, pSVIE26, rhuMab-E25
• Note: For research use only