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MSA-2
Catalog Number: orb1220269
| Catalog Number | orb1220269 |
|---|---|
| Category | Small Molecules |
| Description | MSA-2, a potent and orally available non-nucleotide STING agonist, has EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models. |
| Purity | > 98% (HPLC) |
| MW | 294.3 |
| CAS Number | 129425-81-6 |
| Formula | O=C(C1=CC(C(S1)=C2)=CC(OC)=C2OC)CCC(O)=O |
| Storage | Storage temperature: -20°C. Stability: ≥ 2 years |
| Note | For research use only |
MSA-2 [orb1298624]
98.88%
[129425-81-6]
294.32
C14H14O5S
500 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 2 mg, 1 mg, 1 ml x 10 mM (in DMSO)
