MMV019313

• Catalog Number: orb757603
• Category: Small Molecules
• Description: MMV019313 (MMV 019313, MMV-019313) is a potent, specific malaria bifunctional farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) inhibitor with IC50 of 330 nM; shows no activity against human FPPS or GGPPS (>200 uM); exhibits distinct modes of inhibition compared with bisphosphonates, inhibits P. falciparum growth with EC50 of 268 nM, overexpression and an S228T variant of PfFPPS/GGPPS confer resistance to MMV 019313.
• MW: 397.537
• CAS Number: [902630-14-2]
• Formula: C₂₂H₂₇N₃O₂S
• SMILES: N(C)1C2=C(C=CC=C2)C2SC(C(NCCCN3CCCCCC3)=O)=CC=2C1=O
• Note: For research use only