You have no items in your shopping cart.
Cart summary
Medetomidine
Catalog Number: orb1909168
| Catalog Number | orb1909168 |
|---|---|
| Category | Small Molecules |
| Description | Medetomidine (Domtor) is a potent, highly selective α2-adrenoceptor agonist, demonstrating Ki values of 1.08 nM for α2-adrenoceptors and 1750 nM for α1-adrenoceptors, indicating significant selectivity for α2 over α1 receptors compared to clonidine and UK 14,304 with 1620-, 220-, and 300-fold respectively. Medetomidine significantly inhibits the twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0), showcasing its efficacy. Exhibiting a wide range of pharmacological effects, Medetomidine is effective in vivo, manifesting hypotensive, bradycardic, sedative, anxiolytic, hypothermic, and analgesic properties. |
| Purity | 98.00% |
| MW | 200.28 |
| Biological Activity | Medetomidine (Domtor) is a potent, highly selective α2-adrenoceptor agonist, demonstrating Ki values of 1.08 nM for α2-adrenoceptors and 1750 nM for α1-adrenoceptors, indicating significant selectivity for α2 over α1 receptors compared to clonidine and UK 14,304 with 1620-, 220-, and 300-fold respectively. Medetomidine significantly inhibits the twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0), showcasing its efficacy. Exhibiting a wide range of pharmacological effects, Medetomidine is effective in vivo, manifesting hypotensive, bradycardic, sedative, anxiolytic, hypothermic, and analgesic properties. |
| CAS Number | [86347-14-0] |
| Formula | C13H16N2 |
| SMILES | C(C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2 |
| Storage | -20°C |
| Note | For research use only |
Medetomidine hydrochloride [orb1300641]
96.72%
[86347-15-1]
236.74
C13H16N2·HCl
100 mg, 50 mg, 25 mg, 10 mg, 1 ml x 10 mM (in DMSO), 500 mg
