MC3343

• Catalog Number: orb2814381
• Category: Small Molecules
• Description: MC3343, a DNMT inhibitor with IC50 values of 5.7 μM for DNMT1 and 1.7 μM for DNMT3a, affects tumor proliferation by blocking osteosarcoma cells in the G1 or G2/M phase and induces osteogenic differentiation by specifically re-expressing genes that regulate this physiological process, and is able to show synergistic effects in combination with adriamycin and cisplatin (CDDP).
• Purity: 99.73%
• MW: 461.52
• CAS Number: 1535187-91-7
• Formula: C₂₇H₂₃N₇O
• SMILES: O=C(NC=1C=CC=C(C1)NC2=NC(=NC(=C2)C)N)C=3C=CC=C(C3)NC=4C=CN=C5C=CC=CC54
• Storage: -20°C
• Note: For research use only