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Catalog Number | orb1301314 |
---|---|
Category | Small Molecules |
Description | Loureirin A |
Purity | 99.84% |
MW | 286.32 |
Biological Activity | Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs. |
CAS Number | [119425-89-7] |
Formula | C17H18O4 |
SMILES | COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1 |
Storage | -20°C |
Note | For research use only |
> 98% (HPLC) | |
119425-89-7 | |
286.3 | |
C17H18O4 |