LL-K12-18

• Catalog Number: orb2664307
• Category: Small Molecules
• Description: LL-K12-18 is a bispecific molecular glue that enhances the protein-protein interaction between the CDK12-DDB1 complex, stabilizing the complex and thereby promoting the degradation of cyclin K (IC50=0.37 nM). This compound exhibits potent transcriptional repression and antiproliferative effects in tumor cells. LL-K12-18 is suitable for cancer research applications.
• Purity: 98.00%
• MW: 559.49
• SMILES: O=C(CN(CC)CC)N(CC1)CCN1C2=NC(NCC3=NC4=CC(Cl)=C(Cl)C=C4N3)=C5C(N(CC)C=N5)=N2
• Formula: C₂₅H₃₂Cl₂N₁₀O
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.