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Catalog Number | orb2277236 |
---|---|
Category | Small Molecules |
Description | LL-37(17-32) is a biologically active peptide fragment derived from the C-terminal domain of human cathelicidin antimicrobial peptide. This segment reverses ABCG2-mediated multidrug resistance in cancer cell lines, highlighting its potential therapeutic role against drug resistance. |
Purity | 98.00% |
MW | 2045.48 |
Biological Activity | LL-37(17-32) is a biologically active peptide fragment derived from the C-terminal domain of human cathelicidin antimicrobial peptide. This segment displays a reversal effect on ABCG2-mediated multidrug resistance in cancer cell lines, signifying its potential therapeutic role in combating drug resistance. |
CAS Number | 717919-61-4 |
Formula | C95H161N29O21 |
SMILES | [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)N)=O)CCCCN)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)C(C)C)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)CCCCN)=O)CC(O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)CC(C)C)=O)CC(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |