JBI-589

• Catalog Number: orb2278219
• Category: Small Molecules
• Description: JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors.
• Target: Others
• MW: 481.56
• CAS Number: 2308504-22-3
• Formula: C₂₉H₂₈FN₅O
• SMILES: C(N1C(=CC=2C1=CC=CC2)C3=C(C)N4C(=N3)C=C(C(=O)N5C[C@H](N)CCC5)C=C4)C6=CC=C(F)C=C6
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.