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Catalog Number | orb1709412 |
---|---|
Category | Small Molecules |
Description | Indirubin-5-sulfonate |
CAS Number | 244021-67-8 |
Purity | 98% |
MW | 342.33 |
SMILES | O=C1C(C=2C(N1)=CC=C(S(=O)(=O)O)C2)=C3C(=O)C=4C(N3)=CC=CC4 |
Formula | C16H10N2O5S |
Biological Activity | Indirubin-5-sulfonate shows inhibitory activity against GSK-3β. Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |