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Catalog Number | orb107812 |
---|---|
Category | Proteins |
Description | This E2 enzyme encodes for the human homolog of the yeast DNA repair gene RAD6, which is induced by DNA damagingagents. UBE2B can conjugate ubiquitin to histone H2A in an E3- independent manner in vitro, and is essential for the multiubiquitinationand degradation of N-end rule substrates. Additionally, UBE2B may have a role in sepsis-induced muscle proteinproteolysis and cancer-induced cachexia. |
Target | UBC2 |
Conjugation | Unconjugated |
Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4 |
Purity | > 95% by SDS-PAGE and HPLC analyses |
Protein Sequence | MHHHHHHAMG QLRSMSTPAR RRLMRDFKRL QEDPPVGVSG APSENNIMQWNAVIFGPEGT PFEDGTFKLV IEFSEEYPNK PPTVRFLSKM FHPNVYADGS ICLDILQNRWSPTYDVSSIL TSIQSLLDEP NPNSPANSQA AQLYQENKRE YEKRVSAIVE QSWNDS |
MW | 19.0 kDa |
Tested applications | HPLC, SDS-PAGE |
Biological Origin | E.coli |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Alternative names | Human Ubiquitin Conjugating Enzyme E2 B, His prote Read more... |
Note | For research use only |
SDS-PAGE analysis of Human UBC2 protein
ELISA, WB | |
Greater than 95% as determined by SDS-PAGE | |
16.6 kDa | |
E.Coli |
ELISA, WB | |
Greater than 95% as determined by SDS-PAGE | |
16.6 kDa | |
E.Coli |
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
Escherichia Coli |
Greater than 95% as determined by SDS-PAGE. | |
Escherichia Coli |