You have no items in your shopping cart.
Cart summary
Item 1 of 1
Human sFasR protein
Catalog Number: orb107710
| Catalog Number | orb107710 |
|---|---|
| Category | Proteins |
| Description | Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively.Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases thencleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis byacting as a decoy receptor that serves as a sink for FasL |
| Target | sFasR |
| Conjugation | Unconjugated |
| Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Purity | > 95% by SDS-PAGE and HPLC analyses |
| Protein Sequence | RLSSKSVNAQ VTDINSKGLE LRKTVTTVET QNLEGLHHDG QFCHKPCPPG ERKARDCTVNGDEPDCVPCQ EGKEYTDKAH FSSKCRRCRL CDEGHGLEVE INCTRTQNTK CRCKPNFFCNSTVCEHCDPC TKCEHGIIKE CTLTSNTKCK EEGSRSN |
| MW | 17.6 kDa |
| Tested applications | HPLC, SDS-PAGE |
| Biological Origin | E.coli |
| Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Note | For research use only |
SDS-PAGE analysis of Human sFasR protein
