Human IL-23R Protein, Fc Tag

• Catalog Number: orb570284
• Category: Proteins
• Description: Human IL-23 R, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 355 (Accession # Q5VWK5-1).
• Target: IL-23R
• Conjugation: Unconjugated
• Tag: C-Fc
• Reactivity: Human
• Form/Appearance: Powder
• Buffer/Preservatives: Tris with Glycine, Arginine and NaCl, pH 7.5
• Purity: 95%
• Protein Sequence: NP_653302.2
• UniProt ID: Q5VWK5
• MW: 64.5 kDa
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.5 kDa. The protein migrates as 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression System: HEK293
• Endotoxins: 1.0 EU per μg
• Biological Origin: Human
• Biological Activity: Captured Human IL-23 R, Fc Tag (Cat. No. ) on CM5 chip via anti-human IgG Fc antibodies surface can bind Human IL23A & IL12B, His Tag (Cat. No. ILB-H52W5)with an affinity constant of 5.36 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
• Expression Region: Gly 24 - Gly 355
• Storage: -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
• Note: For research use only
• NCBI: NP_653302.2

Captured Human IL-23 R, Fc Tag (Cat. No. orb570284) on CM5 chip via anti-human IgG Fc antibodies surface can bind Human IL23A & IL12B, His Tag with an affinity constant of 5.36 nM as determined in a SPR assay (Biacore T200) (Routinely tested).