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| Catalog Number | orb2665501 |
|---|---|
| Category | Small Molecules |
| Description | HC-5404-Fu is an inhibitor of PERK with anti-tumor activity. This compound inhibits the signaling pathway of the endoplasmic reticulum stress response. Additionally, HC-5404-Fu increases the sensitivity of renal cell carcinoma cells to vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitors (TKIs). It holds potential for research into renal cell carcinoma, stomach cancer, metastatic breast cancer, small cell lung cancer, and other solid tumors. |
| Target | PERK |
| MW | 570.54 |
| CAS Number | 3034479-99-4 |
| Formula | C28H28F2N4O7 |
| SMILES | C(=C/C(O)=O)\C(O)=O.CC1=C(C=2C=C(C(NC(C)C)=O)C(N)=NC2)C=CC(NC([C@H](O)C3=CC(F)=CC(F)=C3)=O)=C1 |
| Storage | -20°C |
| Research Area | Cell Biology |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)