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Catalog Number | orb1219734 |
---|---|
Category | Small Molecules |
Description | GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).GW7647 (50 nM) stimulates the PI3K phosphorylation followed by the Akt (Ser473) phosphorylation, which causes NOS1 phosphorylation increased the amounts of NO released in the stripped antral mucosa. |
Target | PPARα|PPARγ|PPARδ |
Purity | > 98% (HPLC) |
MW | 502.8 |
CAS Number | 265129-71-3 |
Formula | C29H46N2O3S |
Storage | Storage temperature: -20°C. Stability: ≥ 2 years |
Note | For research use only |