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Granzyme B/GZMB Protein, Mouse, Recombinant (His)
Catalog Number: orb1961531
| Catalog Number | orb1961531 |
|---|---|
| Category | Proteins |
| Description | Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
| Tag | C-6xHis |
| Purity | 98.00% |
| MW | 35 KDa (reducing condition) |
| UniProt ID | P04187 |
| Protein Sequence | Gly19-Ser247 |
| Expression System | HEK293 Cells |
| Biological Origin | Mouse |
| Biological Activity | Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
| Expression Region | Gly19-Ser247 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
