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GPX4-IN-7
Catalog Number: orb2277694
| Catalog Number | orb2277694 |
|---|---|
| Category | Small Molecules |
| Description | GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits HCT-116 cell growth with an IC50 of 0.49 μM. This compound also facilitates GPX4 degradation, leading to lipid ROS accumulation, thereby inducing ferroptosis [1]. |
| Purity | 98.00% |
| MW | 478.93 |
| Formula | C25H23ClN4O4 |
| Biological Activity | GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits HCT-116 cell growth with an IC50 of 0.49 μM. This compound also facilitates GPX4 degradation, leading to lipid ROS accumulation, thereby inducing ferroptosis [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
