Gefitinib

• Catalog Number: orb1309499
• Category: Small Molecules
• Description: Gefitinib
• CAS Number: 184475-35-2
• Purity: 100.00%
• MW: 446.9
• SMILES: N(C=1C2=C(C=C(OC)C(OCCCN3CCOCC3)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4
• Formula: C₂₂H₂₄ClFN₄O₃
• Biological Activity: Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.