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FMF-04-159-2

FMF-04-159-2

Catalog Number: orb2815841

DispatchUsually dispatched within 5-10 working days
$ 150.00
Catalog Numberorb2815841
CategorySmall Molecules
DescriptionFMF-04-159-2 is a potent covalent cell cycle protein-dependent kinase 14 (CDK14) inhibitor with IC₅₀ of 39.6 nM for CDK14 and 256 nM for CDK2.FMF-04-159-2 is able to reduce α-synuclein (α-Syn ) aggregation in neurons and plays a role in Parkinson's disease models, and also inhibits triple-negative breast cancer (TNBC) progression and metastasis by attenuating Wnt/β-catenin signaling.
Purity96.57%
MW683.01
CAS Number2364489-81-4
FormulaC28H30Cl3N7O5S
SMILESN(C(=O)C1=C(Cl)C=C(Cl)C=C1Cl)C=2C(C(NC3CCN(S(=O)(=O)C4=CC(NC(/C=C/CN(C)C)=O)=CC=C4)CC3)=O)=NNC2
Storage-20°C
NoteFor research use only
  • FMF-04-159-2 [orb611957]

    [2364489-81-4]

    683.0057

    C28H30CL3N7O5S

    10 mg, 25 mg, 50 mg