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| Catalog Number | orb2278508 |
|---|---|
| Category | Small Molecules |
| Description | Firazorexton hydrate (TAK-994) is a brain-penetrant, orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM, effectively reducing wakefulness fragmentation and cataplexy-like episodes in mouse models of narcolepsy. |
| Target | Others |
| MW | 497.53 |
| CAS Number | 2861934-86-1 |
| Formula | C22H25F3N2O4S.3/2H2O |
| SMILES | C([C@@H]1N(C(C(C)(C)O)=O)CC[C@@H]1NS(C)(=O)=O)C2=C(F)C(=CC=C2)C3=CC(F)=CC(F)=C3.O |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)