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Catalog Number | orb1300133 |
---|---|
Category | Small Molecules |
Description | EURYCOMANONE |
CAS Number | 84633-29-4 |
Purity | 99.91% |
MW | 408.4 |
SMILES | CC1=CC(=O)[C@@H](O)[C@]2(C)[C@H]3[C@@]4(O)OC[C@@]33[C@@H](C[C@@H]12)OC(=O)[C@H](O)[C@@]3(O)C(=C)[C@H]4O |
Formula | C20H24O9 |
Biological Activity | Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell proliferation in a dose-dependent manner at concentrations ranging from 5 to 20 μg/ml. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |