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| Catalog Number | orb2646295 |
|---|---|
| Category | Small Molecules |
| Description | Endo CNTinh-03 effectively inhibits the increase of cAMP and cGMP triggered by agonists such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase, with an IC50 of 4 μM. It also blocks the chloride ion currents induced by cholera toxin and Escherichia coli (STa) toxins, alleviates secretory diarrhea in mouse models, and prevents cyst growth in models of polycystic kidney disease. |
| Target | PDE |
| MW | 427.51 |
| CAS Number | 345288-49-5 |
| Formula | C23H25NO5S |
| SMILES | O=C(OC)C1=C(SC(=C1C2=CC=C(C=C2)C)C)NC(=O)C3C(C(=O)O)C4CCC3C4 |
| Storage | -20°C |
| Research Area | Metabolism Research |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)