EGFR mutant-IN-1

• Catalog Number: orb1992869
• Category: Small Molecules
• Description: EGFR mutant- in-1, A 5-methylpyrimidopyridone derivative are effective selective EGFRL858R/T790M/C797S mutant inhibitors with IC50 of 27.5 nM, which significantly weakened EGFRWT effect.
• Target: EGFR
• MW: 632.17
• Formula: C₃₄H₃₉ClFN₇O₂
• SMILES: O=C1C(C2=CC=CC(F)=C2Cl)=C(C)C3=CN=C(NC4=CC=C(N5CCN(C)CC5)C(C)=C4)N=C3N1[C@H]6CN(C(CC)=O)CCC6
• Storage: -20°C
• Research Area: Cardiovascular Research, Signal Transduction
• Note: For research use only
• Expiration Date: 12 months from date of receipt.