Echinatin

• Catalog Number: orb1303555
• Category: Small Molecules
• Description: Echinatin
• CAS Number: 34221-41-5
• Purity: 98.12%
• MW: 270.28
• SMILES: COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1
• Formula: C₁₆H₁₄O₄
• Biological Activity: Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.