DS-003

• Catalog Number: orb2815686
• Category: Small Molecules
• Description: DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.
• MW: 478.5
• CAS Number: 676489-50-2
• Formula: C₂₇H₂₂N₆O₃
• SMILES: N#CC(C=1C=CC=CC1)=C2CCN(C(=O)C(=O)C3=CNC=4C(=NC=C(OC)C34)C=5N=CC=NC5)CC2
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.