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Catalog Number | orb692040 |
---|---|
Category | Small Molecules |
Description | Dip G is a natural compound, novel chemical probe reciprocally stabilizes ERβ and destabilizes ERα in breast cancer cells; targets CHIP ubiquitin E3 ligase to modulate ER protein stability, enhances the transcription and anti-proliferative activities of ERβ, while attenuating the transcription and proliferative effects of ERα; the first small molecule that can restore the balance of ERα and ERβ. |
CAS Number | [1190948-58-3] |
MW | 360.321 |
SMILES | O1C(C2=CC=C(O)C=C2)=C2C3=C(C(O)=CC(O)=C3)C(=O)C3=C2C1=CC(O)=C3 |
Formula | C21H12O6 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |