Dinutuximab

• Catalog Number: orb1290219
• Category: Antibodies
• Description: Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions of human IgG1 heavy-chain and kappa light-chain
• Target: ganglioside GD2
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: IgG1-kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: PBS buffer pH 7.5
• Purity: > 95%
• MW: 145000.0 Da
• Tested applications: SDS-PAGE
• Antibody Type: Biosimilar Antibody
• Source: CHO cells
• CAS Number: 1363687-32-4
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks). Store at -20 °C 12 months. Store at -80°C long term
• Alternative names: 14.18, MAb-14.18, MOAB Ch14.18
• Note: For research use only

CAS Number: 1363687-32-4