Dalotuzumab Biosimilar（Anti-IGF1R / CD221 Reference Antibody）

• Catalog Number: orb2703822
• Category: Antibodies
• Description: Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.
• Target: Dalotuzumab Biosimilar（Anti-IGF1R / CD221 Reference Antibody）
• Clonality: Recombinant
• Conjugation: Unconjugated
• Antibody Type: Recombinant Antibody
• CAS Number: [1005389-60-5]
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only