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Catalog Number | orb1304015 |
---|---|
Category | Small Molecules |
Description | Cutamesine dihydrochloride |
Purity | 98.83% |
MW | 441.43 |
Biological Activity | Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo. In a rat model of experimental stroke, it enhances brain plasticity and sensorimotor function. |
CAS Number | [165377-44-6] |
Formula | C23H32N2O2·2HCl |
SMILES | Cl.Cl.COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC |
Storage | -20°C |
Note | For research use only |
> 98% (HPLC) | |
165377-44-6 | |
441.4 | |
C23H32N2O2·2HCl |