CDK4/6-IN-17

• Catalog Number: orb2278189
• Category: Small Molecules
• Description: CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, exhibiting potent activity with IC50 values between 10-100 nM in BE(2) cells, and has demonstrated efficacy in inhibiting tumor growth in the COLO205 xenograft model [1].
• Purity: 98.00%
• MW: 540.56
• Biological Activity: CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, demonstrating potent activity with IC50 values between 10-100 nM in BE(2) cells. It has shown efficacy in inhibiting tumor growth in the COLO205 xenograft model [1].
• CAS Number: 2035069-96-4
• Formula: C₂₇H₂₈F₄N₈
• SMILES: C(F)(F)[C@H]1N2C=3C(N=C2CC1)=C(F)C=C(C3)C4=NC(NC5=CC=C(CN6CCN(CC)CC6)C=N5)=NC=C4F
• Storage: -20°C
• Note: For research use only