CB-002

• Catalog Number: orb692137
• Category: Small Molecules
• Description: CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells.
• MW: 271.28
• CAS Number: [61034-15-9]
• Formula: C₁₃H₁₃N₅O₂
• SMILES: N1C2=C(N(C)C(=O)N(C)C2=O)N=C1NC1=CC=CC=C1
• Note: For research use only