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Catalog Number | orb1299109 |
---|---|
Category | Small Molecules |
Description | Avacopan |
CAS Number | 1346623-17-3 |
Purity | 99.90% |
MW | 581.64 |
SMILES | C(=O)(N1[C@H]([C@@H](C(NC2=CC(C(F)(F)F)=C(C)C=C2)=O)CCC1)C3=CC=C(NC4CCCC4)C=C3)C5=C(C)C=CC=C5F |
Formula | C33H35F4N3O2 |
Biological Activity | Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |