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ARV-825

ARV-825

Catalog Number: orb1301793

DispatchUsually dispatched within 3-5 working days
$ 160.00
Catalog Numberorb1301793
CategorySmall Molecules
DescriptionARV-825
CAS Number1818885-28-7
Purity97.54%
MW923.43
SMILESCC=1C2=C(N3C([C@H](CC(NC4=CC=C(OCCOCCOCCOCCNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)C=C4)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C
FormulaC46H47ClN8O9S
Biological ActivityARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • ARV-825 [orb610506]

    ≥99%

    1818885-28-7

    923.44

    1 mg, 25 mg, 5 mg
  • ARV-825 [orb573167]

    306.33

    C19H15FN2O

    1 g, 100 mg, 250 mg, 1 ml x 10 mm (in DMSO)
  • ARV-825 [orb1890893]

    1818885-28-7

    5 mg
  • ARV-825 [orb1890895]

    1818885-28-7

    10 mg
  • ARV-825 [orb1890892]

    1818885-28-7

    50 mg