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Catalog Number | orb1821020 |
---|---|
Category | Antibodies |
Description | CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers. |
Clonality | Monoclonal |
Clone Number | UP-H2 |
Tested applications | FC |
Reactivity | Human |
Isotype | Mouse IgG1 kappa |
Immunogen | CD300e-HA-transfected cells |
Conjugation | FITC |
Target | CD300e |
Entrez | 342510 |
UniProt ID | Q496F6 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Alternative names | CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2 Read more... |
Note | For research use only |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Expiration Date | 12 months from date of receipt. |
Separation of human monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD300e (UP-H2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD300e (UP-H2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).