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Item 1 of 6
Anti-CDH17 / Cadherin-17 Reference Antibody (10C12)
Catalog Number: orb1818306
| Catalog Number | orb1818306 |
|---|---|
| Category | Antibodies |
| Description | Recombinant Antibody |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Form/Appearance | Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column. |
| Concentration | 1mg/ml |
| Protein Sequence | CDH17 / Cadherin-17 |
| UniProt ID | Q12864 |
| MW | 143.68 |
| Tested applications | ELISA, FC |
| Antibody Type | Primary Antibody |
| Expression System | CHO Cell |
| Endotoxins | < 0.001EU/μg,determined by LAL method. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles |
| Alternative names | Cadherin-17, Intestinal peptide-associated transpo Read more... |
| Note | For research use only |
The purity of Anti-CDH17 / Cadherin-17 Reference Antibody (10C12) is more than 98.15%, determined by SEC-HPLC.
Immobilized human CDH17, His Tag at 2 µg/mL can bind Anti-CDH17 / Cadherin-17 Reference Antibody (10C12), EC50=0.00468 µg/mL
10C12 inhibited the tumor growth of COLO205 on nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 70.0% at 5 mpk at D26.
Anti-CDH17 / Cadherin-17 Reference Antibody (10C12) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
The endocytosis ratio 10C12 by Human CDH17 HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 80% at antibody concentration of 2 nM.
Human CDH17 HEK293 cells were stained with Anti-CDH17 / Cadherin-17 Reference Antibody (10C12) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC240=0.06889 µg/mL
