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AC-264613

AC-264613

Catalog Number: orb1690013

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Catalog Numberorb1690013
CategorySmall Molecules
DescriptionAC-264613
Purity98.00%
MW400.28
Biological ActivityAC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613(AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 30 to 100 nM.
CAS Number1051487-82-1
FormulaC19H18BrN3O2
SMILESCC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1
Storage-20°C
NoteFor research use only
  • AC-264613 [orb1223443]

    > 98% (HPLC)

    1051487-82-1

    400.3

    C19H18BrN3O2

    100 mg, 5 mg, 10 mg, 25 mg, 1 g, 500 mg, 200 mg