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Catalog Number | orb1690013 |
---|---|
Category | Small Molecules |
Description | AC-264613 |
Purity | 98.00% |
MW | 400.28 |
Biological Activity | AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613(AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 30 to 100 nM. |
CAS Number | 1051487-82-1 |
Formula | C19H18BrN3O2 |
SMILES | CC(=NNC(=O)[C@@H]1[C@H](CNC1=O)c1ccccc1)c1cccc(Br)c1 |
Storage | -20°C |
Note | For research use only |
> 98% (HPLC) | |
1051487-82-1 | |
400.3 | |
C19H18BrN3O2 |