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Wnt3a Protein, Human, Recombinant (His)
Catalog Number: orb1977956
| Catalog Number | orb1977956 |
|---|---|
| Category | Proteins |
| Description | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube. Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro). Wnt3a Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.3 kDa and the accession number is P56704. |
| Tag | N-6xHis |
| Purity | 92.00% |
| Protein Sequence | SYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQECTRVYDVHTC |
| UniProt ID | P56704 |
| MW | 41.3 kDa (predicted) |
| Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube. Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro). Wnt3a Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.3 kDa and the accession number is P56704. |
| Expression Region | 19-351 aa |
| Storage | -20°C |
| Note | For research use only |
Recombinant Human WNT3A Protein, N-His [orb2835675]
> 90% as determined by SDS-PAGE.
39.75 kDa
100 μg, 50 μg, 20 μgRecombinant human Wnt3a protein,N-His (E. coli) [orb2328300]
> 90% as determined by SDS-PAGE
40 kDa
500 μg, 10 μg, 50 μgR-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) [orb1957551]
98.20%
15.3 kDa (predicted); 22-27 kDa (reducing condition, due to glycosylation)
1 mg, 50 μg
