Virology & Assay Development

Variant Spike Proteins

High-purity recombinant Trimeric Spike proteins covering Alpha, Beta, Delta, Gamma, and B1.617 mutations.

Isolated recombinant Spike Proteins from COVID-19 variants of concern are now actively available from Biorbyt, manufactured meticulously on a proprietary mammalian protein expression platform.

This highly specialized technology deliberately focuses on rigorous codon optimization and the incredibly stable expression of large molecular weight viral proteins.

The Power of Trimeric Architecture

• Uniquely expressed large MW proteins biologically possessing extensive, native post-translational modifications achieved via codon-optimised sequences in proprietary expression plasmids.
• Super stable trimeric Spikes act efficiently as highly abundant capture antigens, ensuring the most faithful, low-background detection of circulating specific anti-SARS-CoV-2 antibodies in clinically recovered or vaccinated patients.

1. Validation Data

Review our comprehensive SDS-PAGE validation data confirming the high purity and structural stability of our isolated variant Spike proteins.

SARS-CoV-2 trimeric soluble full-length Spike protein, Alpha variant, S protein

SARS-CoV-2 trimeric soluble full-length Spike protein, Beta variant, S protein

Standard Assay Curve: SARS-CoV-2 trimeric soluble full-length Spike protein, Beta variant

SDS-PAGE of SARS-CoV-2 trimeric soluble full-length Spike protein, Delta variant, S protein

SDS-PAGE of SARS-CoV-2 trimeric soluble full-length Spike protein, Gamma variant, S protein

SDS-PAGE of SARS-CoV-2 trimeric soluble full-length Spike protein, B1.617 cluster, S protein

2. Variant Protein Catalog

Browse our selection of highly purified, sequence-accurate isolated recombinant proteins covering the most critical circulating COVID-19 variants of concern.

Name	Catalog #	Application
SARS-CoV-2 trimeric soluble full-length Spike protein, Alpha variant, S protein	orb864241	SDS-PAGE, ELISA
SARS-CoV-2 trimeric soluble full-length Spike protein, Beta variant, S protein	orb864237	SDS-PAGE, ELISA
SARS-CoV-2 trimeric soluble full-length Spike protein, Gamma variant, S protein	orb864238	SDS-PAGE, ELISA
SARS-CoV-2 trimeric soluble full-length Spike protein, Delta variant, S protein	orb864240	SDS-PAGE, ELISA
SARS-CoV-2 trimeric soluble full-length Spike protein, B1.617 cluster, S protein	orb864239	SDS-PAGE, ELISA