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Catalog Number | orb27796 |
---|---|
Category | Antibodies |
Description | Mouse monoclonal antibody to THOC1 is expressed in various cancer cell lines. It participates in an apoptotic pathway, which is characterized by activation of caspase-6, increases in the expression of BAK1 and BCL2L1 and activation of NF-kappa-B. THOC1 contains one death domain and is a component of the heteromultimeric THO/TREX (transcription/export) complex along with THOC2, THOC3, BAT1 and ALY. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 301CT40.5.1 |
Tested applications | WB |
Predicted Reactivity | Mouse |
Reactivity | Human |
Isotype | IgG3,k |
Immunogen | Synthetic Peptide |
Dilution range | WB: 1:100-250 |
Form/Appearance | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Conjugation | Unconjugated |
MW | 75666 |
Target | THOC1 |
UniProt ID | Q96FV9 |
NCBI | NP_005122.2 |
Alternative names | Anti-THO complex subunit 1 antibody, anti-THOC1 an Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Polyclonal | |
Unconjugated |
ChIP, ELISA, IHC, WB | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
IF, IH, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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