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Product Overview
Product Name Tau antibody
Catalog Number orb256674
Species/HostRabbit
ReactivityCanine, Human, Monkey, Mouse, Porcine, Rat
ConjugationUnconjugated
Custom conjugations
Tested applicationsICC, IF, IHC-P, WB
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TAU (pS356). The exact sequence is proprietary. Please contact us for the immunogen region. The peptide is available as orb256964.
Target Tau. Recognizes endogenous levels of TAU (pS356) protein.
Alternative Names
Product Properties
Form/Appearance Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Storage Store at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Note For research use only.
Isotype IgG
ClonalityPolyclonal
Purity The antibody was purified by immunogen affinity chromatography.
Uniprot ID P10636 (Human); P10637 (Mouse); P19332 (Rat)
Entrez 4137
Product Description

Rat polyclonal antibody to Tau having MW of 82 kD that helps stabilize microtubules in our body. On splicing MAPT one can obtain tau protein. Majority of them are found in the CNS region within the neurons but they are not abundant in astrocytes and oligodendrocytes. Tau proteins exist as six different isoforms in brain tissue. These can be distinguished from each other based on their binding domains. If tau protein is no longer functioning we may develop disorders that affect the nervous system such as Alzheimer's and Parkinson's disease. These proteins are very rarely found in non-neuronal cells and are mainly active in the axon part of the neuron.

Application Notes
Dilution Range WB: 1:500-1000, IHC-P: 1:100-200, IF/ICC: 1:100-500
Validation Images
Western blot analysis of SHSY5Y (Lane1), mouse brain (Lane2), rat brain (Lane3) whole cell using TAU (phospho-S356) antibody
Western blot analysis of SHSY5Y (Lane1), mouse brain (Lane2), rat brain (Lane3) whole cell using TAU (phospho-S356) antibody
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human breast cancer tissue using TAU (phospho-S356) antibody
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human breast cancer tissue using TAU (phospho-S356) antibody
Immunofluorescense analysis of Hela cells lysates using TAU (phospho-S356) antibody
Immunofluorescense analysis of Hela cells lysates using TAU (phospho-S356) antibody
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