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SUR1 antibody

SUR1 antibody

Catalog Number: orb149982

DispatchUsually dispatched within 2-3 weeks
$ 556.00
Catalog Numberorb149982
CategoryAntibodies
DescriptionMouse monoclonal to SUR1 (HRP). Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6. x (6. 1 and 6. 2). The association of four Kir6. x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir6. x potassium channel. Hence the KATP channel monitors the energy balance within the cell..
Species/HostMouse
ClonalityMonoclonal
Clone NumberS289-16
Tested applicationsICC, IHC, WB
ReactivityHamster, Human, Mouse, Rat
IsotypeIgG1
ImmunogenFusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1
Concentration1 mg/ml
Dilution rangeWB (1:1000), IHC (1:1000), ICC/IF (1:100)
ConjugationHRP
MW160kDa
TargetSUR1
Entrez25559
UniProt IDQ09429
NCBINP_037171.2
StorageConjugated antibodies should be stored at 4°C
Buffer/PreservativesPBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Alternative namesAM60008PU-N antibody, ABC36 antibody, Abcc8 antibo
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NoteFor research use only
Application notes1 µg/ml of SMC-409 was sufficient for detection of SUR1 in 20 µg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Expiration Date12 months from date of receipt.
  • SUR1 antibody [orb7031]

    ELISA,  WB

    Canine, Equine, Guinea pig, Porcine

    Human, Mouse, Rat

    Rabbit

    Polyclonal

    Unconjugated

    50 μl, 100 μl, 200 μl
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    Rabbit

    Polyclonal

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  • SUR1/ABCC8 Antibody [orb402415]

    FC,  ICC,  IHC,  WB

    Human, Mouse, Rat

    Rabbit

    Polyclonal

    Unconjugated

    10 μg, 100 μg
  • ABCC8 antibody [orb330321]

    IHC-P,  WB

    Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish

    Canine, Human, Mouse, Porcine, Rat, Zebrafish

    Rabbit

    Polyclonal

    Unconjugated

    100 μl
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