SUMO2 antibody

• Catalog Number: orb134982
• Category: Antibodies
• Description: Rabbit polyclonal to SUMO2. Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 973CT8.1.1
• Tested applications: IF, WB
• Predicted Reactivity: Hamster, Mouse, Porcine
• Reactivity: Human, Rat
• Isotype: IgG2b
• Immunogen: Recombinant Protein
• Dilution range: WB: 1:1000
• Form/Appearance: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Conjugation: Unconjugated
• MW: 10871
• Target: SUMO2
• UniProt ID: P61956
• NCBI: NP_001005849.1, NP_008868.3
• Alternative names: anti SUMO2 antibody, anti SMT3A antibody, anti SMT
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Immunofluorescense analysis of Hela cells using SUMO2 antibody