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    SULT2A1 Protein, Human, Recombinant (His) [Out of stock]

    SULT2A1 Protein, Human, Recombinant (His) [Out of stock]

    Catalog Number: orb1958060

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    Catalog Numberorb1958060
    CategoryProteins
    DescriptionSULT2A1 Protein, Human, Recombinant (His) [Out of stock]
    MW35 kDa (predicted)
    Biological ActivityHydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.
    NoteFor research use only
    Expiration Date6 months from date of receipt.
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