Substance P (2-11)

SKU: orb1943685

Description

This research peptide, Substance P (2-11), is a bioactive fragment that induces contraction in guinea pig ileum and acts as a competitive inhibitor of Substance P transport across the blood-brain barrier in vitro. It is a valuable tool for neuropharmacology studies investigating tachykinin receptor signaling, intestinal motility, and central nervous system permeability.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: Neurokinin receptor
• CAS Number: 53749-61-4
• MW: 1191.44
• Formula: C₅₇H₈₆N₁₄O₁₂S
• SMILES: C([C@@H](NC(=O)[C@@H]1CCCN1)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

14535496