Spike protein (RBD) antibody

• Catalog Number: orb759003
• Category: Antibodies
• Description: Mouse monoclonal antibody to Spike protein (RBD)
• Species/Host: Camelus
• Clonality: Monoclonal
• Clone Number: Sb#42
• Tested applications: ELISA
• Reactivity: Virus
• Isotype: IgG1-Fc Fusion
• Immunogen: This clone was originally isolated in a form of a synthetic nanobody (sybody) via a 'target swap' selection procedure against RBD-vYFP using ribosomal display and against RBD-Fc fusion during phage display rounds.
• Purity: Purified
• Conjugation: Unconjugated
• Target: Spike protein (RBD)
• UniProt ID: P0DTC2
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Receptor Binding Domain; SARS CoV 2 S glycoprotein
• Note: For research use only
• Application notes: This antibody is recommended for detection of SARS CoV 2 or 2019-nCoV. Its high specificity to the novel coronavirus SARS-Cov-2 was confirmed via ELISA testing (Walter et al., 2020). Furthermore, grating-coupled interferometry demonstrated that this antibody binds the receptor binding domain (RBD) of the spike protein with high affinity (Walter et al., 2020). Subsequent testing showed that this clone exhibits exceptionally strong inhibition of binding of SARS-Cov-2 RBD to hACE2, which is the receptor for the virus (signal of RBD association with hACE2 decreased over 90%) (Walter et al., 2020).
• Expiration Date: 12 months from date of receipt.