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Catalog Number | orb154739 |
---|---|
Category | Small Molecules |
Description | S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, > 130-fold selectivity for JAK1/2 versus JAK3. Phase 3. |
CAS Number | [941685-37-6] |
MW | 306.37 |
SMILES | N#CC[C@@H](C1CCCC1)N2N=CC(C3=NC=NC4=C3C=CN4)=C2 |
Formula | C17H18N6 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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