| Catalog Number | orb61091 |
|---|---|
| CAS Number | 186692-46-6 |
| Application notes | ARK |
| Note | For research use only. |
| Expiration Date | 12 months from date of receipt. |
| Description | Roscovitine (Seliciclib, CYC202, R-roscovitine) is a potent and selective CDK inhibitor for Cdc2/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p53 with IC50 of 0.65 μM, 0.7 μM, 0.7 μM and 0.16 μM, respectively. Roscovitine is currently in Phase I clinical trial in patients with advanced solid tumors. |
Chemical structure of Roscovitine, Free Base
Roscovitine, Free Base: Seliciclib, R-Roscovitine, (R)-roscovitine
