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Catalog Number | orb107815 |
---|---|
Category | Proteins |
Description | Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival ofendothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays aprominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumormetastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1),KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. |
Tested applications | HPLC, SDS-PAGE |
Purity | > 95 % by SDS-PAGE and HPLC analyses |
Conjugation | Unconjugated |
MW | 19.4 kDa |
Target | VEGF165 |
Protein Sequence | MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGCCNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPCSERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, 300 mM NaCl, pH 8.8. |
Alternative names | Rat Vascular Endothelial Growth Factor protein Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
Unconjugated | |
95% | |
14.1 kDa | |
Human VEGF121 Protein, premium grade (orb257918) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 147 (Accession # P15692-9). |
Unconjugated | |
95% | |
14.9 kDa | |
Human VEGF121, His Tag (orb334936) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 147 (Accession # P15692-9). |
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