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Catalog Number | orb107773 |
---|---|
Category | Proteins |
Description | gamma -Interferon Inducible Protein 10 (IP-10)/CXCL10 was originally identified as an IFN-gamma-inducible gene in monocytes,fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1beta , TNF-alpha , IL-12 andviruses. Additional cell types that have been shown to express IP-10 include activated T-lymphocytes, splenocytes, keratinocytes,osteoblasts, astrocytes, and smooth muscle cells. IP-10 is also expressed in psoriatic and lepromatous lesions of skin. The mousehomologue of human IP-10, Crg-2, has been cloned andshown to share approximately 67% amino acid sequence identity withhuman IP-10. |
Tested applications | HPLC, SDS-PAGE |
Purity | > 95% by SDS-PAGE and HPLC analyses |
Conjugation | Unconjugated |
MW | 8.6 kDa |
Target | IP-10 |
Protein Sequence | IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEAIKSLLKAVSQ RRSKRAP |
Biological Origin | E.coli |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Rat IP-10 protein
> 95% as determined by SDS-PAGE and HPLC. | |
8.7 kDa | |
E.Coli |
Rat | |
31.25-2000pg/mL | |
18.75pg/mL |